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    National Center for Genome Medicine, the former National Genotyping Center, was established in 2002. The long-term objective of this Center’s project is (1) to establish Taiwan as an international powerhouse in genome medicine research and translational medicine, (2) to provide high-quality, high-throughput genotyping and next-generation sequencing services, (3) to provide web-based, high-performance, cost-effective, and easy-to-use NGS bioinformatics analysis pipelines to investigators of the scientific community and biotech industry in Taiwan.
    Six genome analysis platforms were established, including microsatellite (short tandem repeat polymorphism, STRP) analysis, SNP (single nucleotide polymorphism) analysis using MALDI-TOF (matrix-assisted laser desorption/ionization – time of flight) mass spectrometry technology, oligo-array based technology for ultra-high throughput SNP genotyping (Affymetrix GeneChip and GeneTitan), and next-generation sequencing using Roche GS-FLX Titanium, Illumina HiSeq 2000 and Illumina MiSeq platforms. These genomic technology platforms allow this Center to provide various combinations of services tailored to each investigator’s need. Since August of 2012, this Center has been granted the accreditation certificate of ISO/IEC 17025 for the services listed in the approved scope of accreditation by the Taiwan Accreditation Foundation (TAF).
    In addition to the genotyping and sequencing teams, this Center also has biostatistics and bioinformatics divisions. The former is in charge of quality assurance/quality control of genotyping and sequencing services; the latter is in charge of developing bioinformatics tools and providing bioinformatics services such as on-line tool consultation, bioinformatics data analysis and software development.

Services :

Service Type
Service Code
Service Item
Technology Platform
Sample Management
C2-17
DNA Extraction from 5 mL Whole Blood  
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C2-18
DNA Extraction from 10 mL Whole Blood
C2-19
DNA Storage
C2-26
DNA Extraction from Cultured Cell
SNP Genotyping
C2-7
ENU Mouse Gene Mapping Panel
Sequenom MassARRAY
C2-10
iPLEX SNP Genotyping
C2-12
Mouse Speed Congenics Panel (294 markers & 92 markers)
Whole-Genome SNP Genotyping
C2-14
Affymetrix Genome-Wide Human SNP 6.0
Affymetrix GeneChip
C2-15
Axiom Genome-Wide ASI Array Plate
Affymetrix GeneTitan
C2-16
Axiom Genome-Wide CHB Array Plate
C2-42
Axiom Genome-Wide TWB Array Plate
STRP Genotyping
C2-4
PCR Product STRP Genotyping
ABI 3730 DNA Analyzer
Next Generation Sequencing
C2-27
Human whole genome sequencing, 30X
illumina HiSeq 2000 / illumina MiSeq
C2-29
DNA sequencing sample preparation
C2-30
Paired-end sequencing, 100x2 bp, per lane
C2-36
mRNA sequencing sample preparation
C2-37
rRNA-Depleted RNA sequencing sample preparation
C2-43.1
MiSeq Sequencing Service (50 cycles)
C2-43.2
MiSeq Sequencing Service (150 cycles)
C2-43.3
MiSeq Sequencing Service (300 cycles)
C2-43.4
MiSeq Sequencing Service (300 cycles, Micro)
C2-43.5
MiSeq Sequencing Service (300 cycles, Nano)
C2-43.6
MiSeq Sequencing Service (500 cycles)
C2-43.7
MiSeq Sequencing Service (500 cycles, Nano)
C2-43.8
MiSeq Sequencing Service (600 cycles)
C2-45
Small RNA sequencing sample preparation
C2-46
Paired-end sequencing, 100x2 bp, 10M Reads
C2-47
Library QC
C2-48
SureSelect Exome Enrichment (Human/Mouse)
C2-50
ChIP sequencing sample preparation
C2-51
DNA library sample preparation by Nextera XT
C2-52.1
MiSeq DNA Library QC (qPCR only)
C2-52.2
MiSeq DNA Library QC (Qubit Fluorometer + Agilent Bioanalyzer HS)
C2-52.3
MiSeq DNA Library QC (Qubit Fluorometer + Agilent Bioanalyzer HS + qPCR)
C2-55.1
RNA QC-Agilent RNA 6000 Nano
C2-55.2
DNA QC-Agilent DNA High Sensitivity
BioIT Services
C2-20
Samportal consulting
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C2-21
iQuestion consulting
C2-22
Bioinformatics data analysis, software development and consultation
C2-23
Samportal hosted
C2-24
iQuestion hosted
C2-38
NGS whole genome data analysis
C2-39
NGS Exome data analysis
C2-40
NGS RNA data analysis
C2-49.1
NGS data analysis service
C2-49.2
NGS data storage service
C2-53
Biomedical information management system consulting
C2-54
Biomedical information management system hosted
Statistical Analysis
C2-56
Axiom Array genome-wide association analysis, GWAS
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C2-57
Data management and statistical analysis
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Customized Service
C2-44
Customized Service
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